Description
MASTERON 150 (TOP) 150mg x 10ml/vial
Maronstea
Anabolic/Androgenic Ratio: 62/25
Effective dosage (men) 350-500mg/week (100-150mg/once every 2 days)
Effective dosage (women) 25-50mg/once every 2-3 days
Effective period: 2-3 days
Detection period: 3 weeks
Drostanolone propionate is a prodrug of drostanolone.
Like other AAS, drostanolone is an agonist of the androgen receptor (AR). It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity.
As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites.
While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives. Since the drug is not 17α-alkylated, it is not known to cause hepatotoxicity.
Drostanolone propionate, via its active form drostanolone, interacts with the AR and activates a cascade of genetic changes, including increased protein synthesis (anabolism) and decreased amino acid degradation (catabolism). It also induces a reduction or inhibition of prolactin or estrogen receptors in the breasts, which is linked to its antitumor effects.
